Koichi Nisijima Selected Research

Serotonin Syndrome (Syndrome, Serotonin)

12/2015	Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes.
10/2012	Risperidone attenuates the increase of extracellular nitric oxide and glutamate levels in serotonin syndrome animal models.
10/2010	Mirtazapine abolishes hyperthermia in an animal model of serotonin syndrome.
1/2007	Neuroleptic malignant syndrome and serotonin syndrome.
7/2004	Extracellular serotonin, dopamine and glutamate levels are elevated in the hypothalamus in a serotonin syndrome animal model induced by tranylcypromine and fluoxetine.
7/2004	Possible serotonin syndrome arising from an interaction between caffeine and serotonergic antidepressants.
7/2003	Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome.

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Koichi Nisijima Research Topics

Disease

7	Serotonin Syndrome (Syndrome, Serotonin) 12/2015 - 07/2003
7	Hyperthermia 01/2014 - 07/2003
5	Neuroleptic Malignant Syndrome 12/2015 - 01/2007
2	Major Depressive Disorder (Major Depressive Disorders) 03/2017 - 04/2002
2	Restless Legs Syndrome (Restless Legs) 01/2015 - 12/2006
2	Schizophrenia (Dementia Praecox) 01/2014 - 01/2007
2	Muscle Rigidity 01/2013 - 01/2012
2	Catatonia 01/2013 - 06/2009
1	Rhabdomyolysis 09/2017
1	Hallucinations (Hallucination) 01/2014
1	Hemophilia A (Haemophilia) 01/2014
1	Hemorrhage 01/2014
1	Tachycardia (Tachyarrhythmias) 01/2013
1	Pheochromocytoma 06/2009
1	Infections 06/2008
1	Vomiting 06/2008
1	Nausea 06/2008
1	Drug Fever 01/2007
1	Treatment-Resistant Depressive Disorder 06/2004
1	Poisoning 01/2004

Drug/Important Bio-Agent (IBA)

6	Antipsychotic Agents (Antipsychotics)IBA 12/2015 - 01/2007
5	Antidepressive Agents (Antidepressants)IBA 12/2015 - 04/2002
4	Serotonin (5 Hydroxytryptamine)IBA 01/2014 - 07/2004
4	5-HT1A Serotonin ReceptorIBA 10/2010 - 04/2002
3	Mirtazapine (Rexer)FDA LinkGeneric 01/2015 - 10/2010
3	Creatine Kinase (Creatine Phosphokinase)IBA 01/2014 - 01/2012
3	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 12/2012 - 11/2008
2	perospironeIBA 01/2014 - 06/2004
2	CatecholaminesIBA 01/2013 - 06/2009
2	Glutamic Acid (Glutamate)FDA Link 10/2012 - 07/2004
2	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 10/2010 - 07/2003
2	Dopamine (Intropin)FDA LinkGeneric 07/2004 - 06/2004
2	Fluoxetine (Prozac)FDA LinkGeneric 07/2004 - 06/2004
1	fluphenazine depot (modecate)FDA LinkGeneric 09/2017
1	Pramipexole (Mirapex)FDA LinkGeneric 01/2015
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2014
1	Factor VIII (Coagulation Factor VIII)IBA 01/2014
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 01/2014
1	Biogenic Amines (Biogenic Amine)IBA 01/2013
1	Memantine (Namenda)FDA Link 12/2012
1	Illicit Drugs (Recreational Drugs)IBA 12/2012
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2012
1	Risperidone (Risperdal Consta)FDA LinkGeneric 10/2012
1	Indicators and Reagents (Reagents)IBA 01/2012
1	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 07/2011
1	RitanserinIBA 10/2010
1	Neuraminidase (Sialidase)IBA 06/2008
1	Oseltamivir (Tamiflu)FDA Link 06/2008
1	Tranylcypromine (Parnate)FDA LinkGeneric 07/2004
1	Caffeine (No Doz)FDA LinkGeneric 07/2004
1	iodoformIBA 01/2004
1	Chlormethiazole (Clomethiazole)IBA 07/2003
1	Diazepam (Valium)FDA LinkGeneric 07/2003
1	Buspirone (Buspar)FDA LinkGeneric 04/2002
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 04/2002

Therapy/Procedure

1	Intramuscular Injections 09/2017
1	Transcranial Magnetic Stimulation 03/2017
1	Induced Hyperthermia (Thermotherapy) 07/2011